| Molecular diagnosis and bacterial genotyping |
Dr Janjira Thaipadungpanit from our MORU unit in Bangkok, Thailand, tells us about her research on molecular diagnosis and bacterial genotyping |
Janjira Thaipadungpanit |
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| Biomarkers for tropical diseases |
Dr Markus Winterbert from our MORU unit in Bangkok, Thailand, tells us about his research on biomarkers for tropical diseases |
Markus Winterberg |
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| MORU Biosafety Level 3 and melioidosis in Thailand |
Premjit Amornchai from our MORU unit in Bangkok, Thailand, tells us about her work as biosafety level 3 lab manager and microbioogy safety officer |
Premjit Amornchai |
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| Malaria control in Africa |
Professor Bob Snow from our KEMRI-Wellcome programme in Nairobi, Kenya, tells us how his research brings together epidemiological profiles and government policies to maximise malaria control programmes in Africa |
Bob Snow |
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| Malaria elimination in the Greater Mekong sub-region |
Dr Lorenz von Seidlein from our MORU unit in Bangkok, Thailand, tells us about his research on malaria elimination in the Greater Mekong sub-region |
Lorenz von Seidlein |
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| Tracking infections |
Professor Derrick Crook from our Experimental Medicine division tells us about his research on tracking infections |
Derek Crook |
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| Mapping bacterial antibiotic resistance |
Dr Olga Tosas-Auguet from our unit in Kenya tells us about her research on mapping bacterial antibiotic resistance |
Olga Tosas-Auguet |
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| Bacterial infections in Laos |
David Dance from our LOMWRU unit in Laos tells us about his research on bacterial infections in Laos, particularly melioidosis |
David Dance |
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| Optimising malaria treatment |
Dr Georgina Humphreys coordinates the WorldWide Antimalarial Resistance Network (WWARN) study groups by encouraging partner engagement and managing the data curation and development of publications. |
Georgina Humphreys |
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| Outbreak, the clinical research response |
Dr Gail Carson is Head of ISARIC Coordinating Centre (International Severe Acute Respiratory and Emerging Infection Consortium), a network of networks established in 2011 to ensure a rapid research response to outbreaks of pandemic potential. |
Gail Carson |
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| Epigenetic modifications and cancer |
Professor Skirmantas Kriaucionis aims to to elucidate the molecular function of DNA modifications in normal cells and cancer. |
Skirmantas Kriaucionis |
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| Fighting malaria in Myanmar |
Professor Frank Smithuis is the director of MOCRU, Myanmar Oxford Clinical Research Unit. MOCRU involves a network of 6 clinics and 650 community health workers in remote areas. |
Frank Smithuis |
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| Why we work on Alzheimer’s disease |
Housed within the Target Discovery Institute, the Alzheimer’s Research UK Oxford Drug Discovery Institute (ODDI) juxtaposes drug discovery expertise alongside scientific and academic understanding of patients, disease mechanisms and model systems. |
John Davis |
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| Gastrointestinal cancers |
Dr Claire Palles studies whole genome sequencing data and targeted analyses with the aim of discovering genetic variants that affect susceptibility to colorectal cancer and Barrett’s oesophagus. |
Claire Palles |
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| Poor quality medicines |
LOMWRU researchers conduct clinical research to help improve global, regional and Lao public health. They focus on infectious diseases, and also investigate diseases of nutrition and poverty. |
Paul Newton |
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| High altitude illness |
Director of OUCRU-Nepal, Dr Buddha Basnyat studies high altitude illness as well as undifferentiated febrile illness in the tropics, both common but neglected problems in Nepal. |
Buddha Basnyat |
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| Infectious diseases in Indonesia |
Professor Kevin Baird leads our Eijkman-Oxford Clinical Research Unit (EOCRU) in Jakarta, Indonesia. |
Kevin Baird |
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| Finding the best malaria treatments |
Dr Mehul Dhorda heads the Asia Regional Centre of the WorldWide Antimalarial Resistance Network (WWARN). |
Mehul Dhorda |
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| Evolution and pathogenicity of viruses |
Professor Peter Simmonds studies the epidemiology, evolution and emergence of a wide range of human pathogenic viruses. |
Peter Simmonds |
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| X-rays for drug discovery |
Professor Frank von Delft works to ensure that X-ray structures can serve as a routine and predictive tool for generating novel chemistry for targeting proteins. |
Frank von Delft |
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| Modelling bacterial drug resistance |
Professor Ben Cooper from MORU in Thailand uses mathematical modelling and statistical techniques to help understand the dynamics of infectious disease and evaluate potential control measures. |
Ben Cooper |
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| Epidemiology and malaria elimination |
Dr Richard Maude's work combines clinical studies, descriptive epidemiology and mathematical modelling of malaria in South and Southeast Asia. |
Richard Maude |
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| Why data management matters |
Naomi’s work focuses on supporting researchers to collect, clean and store research data. |
Naomi Waithira |
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| Malaria laboratory at MORU |
Dr Kesinee Chotivanich's laboratory provides facilities and resources to researchers, students, and collaborators who are interested in tropical diseases, with the aim to improve patients’ care. |
Kesinee Chotivanich |
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| From information to structure |
Dr Brian Marsden aims to make structural and chemical biology data accessible to non-experts, by providing computational resources including data management, sample tracking, in silico modelling support plus provision of public access to SGC data. |
Brian Marsden |
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| Repairing DNA damage |
Dr Ross Chapman studies the molecular events triggered by DNA damage detection, and why defects in these events lead to immune deficiency and cancer in humans. |
Ross Chapman |
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| Malaria in Kenya |
There is a great need for better treatments for malaria and for a preventative malaria vaccine. |
Philip Bejon |
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| Microbiology in the tropics |
The Cambodia Oxford Medical Research Unit (COMRU) is based in Siem Reap, northern Cambodia, which remains one of the poorest countries in South East Asia with extremely limited health services. |
Paul Turner |
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| Unravelling proteins |
Dr Nicola Burgess-Brown heads the Biotechnology Group at the SGC, which generates proteins suitable for structural and functional studies. |
Nicola Burgess-Brown |
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| Targeting drug discovery |
The development of new medicines is dependent on the identification of novel drug targets. |
Kilian Huber |
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| Microbiology research in SE Asia |
Dr Direk Limmathurotsakul's research focuses on the epidemiology of melioidosis, a bacterial infection caused by Burkholderia pseudomallei. |
Direk Limmathurotsakul |
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| Tropical neonatology |
Dr Claudia Turner heads the clinical research program at the Cambodia Oxford Medical Research Unit (COMRU), in collaboration with the Angkor Hospital for Children. |
Claudia Turner |
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| Global health informatics |
Dr Chris Paton studies the use of open-source Electronic Health Records (EHR) software, online learning and mobile technology to improve healthcare delivery in low-resource settings. |
Chris Paton |
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| Dengue diagnosis and management |
With 390 million infections occuring each year, dengue is the most important mosquito-borne viral infection, and no vaccine is currently available. |
Bridget Wills |
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| Understanding growth signals |
Growth hormones and cytokines regulate the key physiological processes of growth and differentiation as well as responses to injury and infection. |
Alex Bullock |
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| Malaria in pregnancy |
In pregnant women, severe malaria is responsible for high maternal mortality, and uncomplicated malaria results in in high morbidity. |
Rose McGready |
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| Reducing HIV |
Men who have sex with men (MSM) are a stigmatised group in Africa, but a predominant actor in the transmission of HIV. |
Eduard Sanders |
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| Cleaning up misfolded proteins |
Misfolded proteins can either create the loss of a cellular function, or escape degradation, causing aggregation diseases. |
John Christianson |
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| Rare neurological disorders |
Chorea-Acanthocytosis: ChAc is a rare progressive neurological disorder caused by mutations in a very complex gene. |
Antonio Velayos-Baeza |
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| Targeting cancer mechanisms |
Professor Robert Gilbert's research focuses on the molecular mechanisms underlying membrane pore formation and cell adhesion. |
Robert Gilbert |
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| Inflammation in disease |
The main aim of Dr Xue's research is to understand the molecular and cellular mechanisms mediating inflammatory diseases, and to translate their findings into therapeutic concepts to treat these diseases. |
Luzheng Xue |
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| Computation and genetics |
Resistance to drugs in bacteria can be aquired by swapping genes between individual bacteria. Computer programs developed by Dr Iqbal enable doctors to predict which antibiotics will be met with drug resistance, enabling the selection of the right drug. |
Zamin Iqbal |
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| The Evolution of the Genome |
Computational and stastistical methods help us understand evolution as well as genetic disease. |
Gerton Lunter |
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| Tropical Immunology |
Melioidosis is a neglected tropical disease, and a major infectious killer in South East Asia. Melioidosis particularly affects people with diabetes. |
Susanna Dunachie |
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| Sharing data to fight malaria |
Over 250 Institutions participate in the effort of sharing data on the efficacy of antimalarial drugs, which involves standardising and re-analysing data. |
Philippe Guérin |
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| Artemisinin Resistance |
Artemisinins are very poweful tools in the treatment of malaria, and the emerging loss of their activity has the potential to create a major public health problem. |
Charlie Woodrow |
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| The ethics of research |
Identifying and addressing ethical issues are key to the success of any clinical trials, particularly when working with vulnerable populations. |
Phaik Yeong Cheah |
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| Science and Society |
In settings with high level of poverty and over-stretched health services, researchers have even greater responsibilities to the communities and study participants. |
Vicki Marsh |
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| Melanoma |
Melanoma or skin cancer is one of the fastest rising cancer types. When identified early, melanoma is relatively easy to cure, but once it starts to metastasise, it becomes very difficult to treat. |
Colin Goding |
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| Targeting epigenetics to treat cancer |
Transcription is a tightly regulated process, where chemical modifications initiate the duplication of genetic material. This epigenetic process is often dysregulated in cancer, but it can be targeted with small molecule inhibitors. |
Panagis Filippakopoulos |
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| A deep breath in |
Asthma and COPD (chronic obstructive pulmonary disease) are common conditions that affect the lives of many people. |
Mona Bafadhel |
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| Chemistry, epigenetics and drugs |
Alteration of gene expression is fundamental to many diseases. A better understanding of how epigenetic proteins affect diseases provides a starting point for therapy development and the discovery of new drug. |
Paul Brennan |
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| The genetics of metabolic diseases |
A missing step in a metabolic pathway leads to the build-up of toxic compounds, and the lack of materials essential for normal function. |
Wyatt Yue |
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| The economics of tropical diseases |
Economics and health are interlinked in many ways, as seen in the vicious cycle between poverty and ill health. |
Yoel Lubell |
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| Getting the dose right |
Too high a dose can result in toxicity and side-effects, too low a dose can cause the illness to come back and at worse develop resistance. |
Joel Tarning |
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| Enteric fever |
Dr Christiane Dolecek speaks about the research on enteric fever she conducted in Vietman and Nepal. |
Christiane Dolecek |
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| Emerging Infectious Diseases |
Professor Peter Horby is Senior Clinical Research Fellow. His research focusses on epidemic diseases such as Ebola and bird flu, and crosses the disciplines of basic science, medical science and public health. |
Peter Horby |
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| Human Cancer Genetics |
Dr Gareth Bond, Associate Member of the Ludwig Institute for Cancer Research, studies the influence of genetic variants on the origins, progression and treatment of human cancer. |
Gareth Bond |
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| Personalised Medicine |
Dr Jenny Taylor is the Programme Director for the Genomic Medicine Theme, Wellcome Trust Centre for Human Genetics. Her research bridges the gap between genetics research and the use of its discoveries in diagnosis or treatment of medical conditions. |
Jenny Taylor |
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| Cancer predisposition and evolution |
Identifying genes that increase the risk of bowel or other cancers allows us to offer preventative measures, such as removing tumours at an early stage. A better understanding of how and why cancers grow also helps develop improved treatments. |
Ian Tomlinson |
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| Cancer Informatics |
Cancer research now generates huge amounts of data, and sophisticated computational tools are needed to answer biological questions. Making sense of this variability at molecular level will help us better tailor treatments to individual cancer patients. |
Benjamin Schuster-Böckler |
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| Biological imaging |
Video microscopy aims to improve target discovery and drug development and to do so generates large volumes of data. |
Jens Rittscher |
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| Pharmacogenomics |
Dr Sebastian Nijman develops new approaches to study signalling networks in cancer cells and uncover specific weaknesses, particularly in breast and lung cancer. This can be used to develop more effective drugs and to better guide treatment decisions. |
Sebastian Nijman |
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| Microbiology in Thailand |
Microbiology in Thailand |
Stuart Blacksell |
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| Infectious diseases in South East Asia |
Infectious diseases in South East Asia |
Nick Day |
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| Rickettsial Disease |
Daniel Paris: Rickettsial Disease |
Daniel Paris |
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| Better hospitals for children |
Oxford Health Systems Research Collaboration (OHSCAR) |
Mike English |
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| Health systems research |
Governance in practice |
Sassy Molyneux |
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| Virus entry |
Novel light microscopy techniques allow us to track single viruses. |
Sergi Padilla-Parra |
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| DNA replication and Cancer |
DNA replication and Cancer |
Catherine Green |
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| Big Data |
Over the past decade, data-driven science has produced enormous sets of data. |
Christopher Yau |
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| Between research and humanitarian |
Between research and humanitarian |
Francois Nosten |
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| Tuberculous Meningitis |
Tuberculous Meningitis |
Guy Thwaites |
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| Crohn's disease |
Innate immune system |
Alison Simmons |
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| Structural biology and vaccines |
Structure of viruses |
Dave Stuart |
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| Stem cells and cancer |
Adult gastrointestinal stem cells |
Simon Leedham |
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| Cancer and innate immunity |
Inflammatory signalling |
Mads Gryd-Hansen |
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| Asthma |
Airway inflammation |
Ian Pavord |
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| Pneumococcal diseases |
Genetics and genomics of Streptococcus pneumoniae |
Angela Brueggemann |
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| Active and passive immunity to Influenza |
Professor Townsend tells us about lessons to be drawn from the history of immunology in Oxford, from 1979 onwards, until his current research on active and passive immunity to influenza. |
Alain Townsend |
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| Human Genetics |
Professor Peter Donnelly tells us how genetics helps us to understand common diseases and develop new drugs. |
Peter Donnelly |
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| The Global Health Network |
Dr Trudie Lang tells us how the Global Health Network facilitates collaboration and resource sharing. |
Trudie Lang |
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| Artemisinin therapy for malaria by Professor Nick White |
Professor Nick White talks about the future of artemisinin and other drug therapies for malaria. |
Nick White |
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| Atherosclerosis and immunity by Professor Chris O'Callaghan |
Professor Chris O'Callaghan tells us about the role of our immune system in vascular disease. |
Chris O’Callaghan |
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| Respiratory Medicine |
Dr Najib Rahman talks about his research on respiratory medicine. |
Najib Rahman |
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| Psychiatric genetics |
Professor Jonathan Flint talks about his research on psychiatric genetics. |
Jonathan Flint |
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| Development of chemical probes |
Professor Stefan Knapp tells us how the development of chemical probes helps us to find new drugs. |
Stefan Knapp |
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| Can we block malaria transmission |
Dr Sumi Biswas talks about the development of a vaccine aimed at the mosquito stage of the malaria parasite cycle. |
Sumi Biswas |
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| Membrane proteins and drug development |
Dr Liz Carpenter talks about her research on membrane proteins and drug development. |
Liz Carpenter |
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| MedicineAfrica |
Dr Alexander Finlayson tells us how MedicineAfrica aims to bring healthcare professionals around the world in a global expert network. |
Alexander Finlayson |
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| Structural cell biology of virus infection |
Professor Kay Grunewald tells us how structural cell biology can help us understand virus infection. |
Kay Grunewald |
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| Molecular immunology |
Dr Christian Eggeling tells us how new imaging methods help us understand immunology at the molecular level. |
Christian Eggeling |
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| The lymphatic system in immunity and cancer |
Professor David Jackson tells us about the role of the lymphatic system in immunity and cancer. |
David Jackson |
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| Cutaneous immunology |
Professor Graham Ogg talks about the role of our skin as a barrier against infection. |
Graham Ogg |
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| Fiona Powrie |
Professor Fiona Powrie talks about the importance of our guts, and her research in gastroenterology. |
Fiona Powrie |
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| Clinical Trials in Gastroenterology |
Dr Simon Travis tells us how clinical trials bring tomorrows treatments to patients today. |
Simon Travis |
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| Cancer Immunlogy |
Professor Vincenzo Cerundolo tells us how research in immunology leads to the development of new cancer treatments. |
Vincenzo Cerundolo |
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| Cancer and regenerative medicine |
Professor Xin Lu talks about the links between cancer and regenerative medicine. |
Xin Lu |
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| How the immune system detects flu virus |
Dr Jan Rehwinkel talks about the role of our innate immune system in our fight against flu virus. |
Jan Rehwinkel |
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| Can we eradicate HIV? |
Dr John Frater talks about his research into finding a cure for HIV. |
Dr John Frater |
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